11th MAP seminar

2022.09.09 お知らせ

11th MAP Seminar Report

Date: September 9, 2022

Speaker: Dr. Sakura, Dr. Fu, and Dr. Matsumoto

We held our 11th MAP seminar on September 9, 2022. A total of 16 members participated in this seminar. Three members presented their research in English, Dr. Sakura, Dr. Fu, and Dr. Matsumoto.

The first was Dr. Sakura, whose study was on the association of plasma free hemoglobin (PFH) and postoperative acute kidney injury in pediatric cardiac surgery. He took plasma free hemoglobin at different time points intraoperatively and postoperatively, as well as defined the incidence of postoperative acute kidney injury using the KDIGO guidelines. The results were that peak PFH was different in the AKI and non-AKI patient, but the maximum PFH was not associated with AKI in multivariate regression, possibly suggesting that other factors may be more associated with AKI than plasma free hemoglobin produced by hemolysis in the younger cohorts. We were very interested in this novel topic and many questions were asked enthusiastically. We look forward to the new information Dr. Sakura will share with us next time.

Next up was Dr. Fu with her study on the Impact of different KDIGO criteria on clinical outcomes for early identification of acute kidney injury after non-cardiac surgery. Her study focused on the use of creatinine and urine output criteria in the KDIGO guidelines and how different methods of calculating urine output produce different diagnostic criteria, which can lead to large differences in the incidence and prognosis of postoperative AKI. The study was of great interest to the audience, who asked questions about the limitations of the urine output criteria in clinical practice in the KDIGO guidelines and about the impact of diuretic use on the diagnosis, to which Dr. Fu responded, indicating that if the clinical diagnosis of AKI is made using only creatinine criteria, this may lead to underdiagnosis of patients with oliguric AKI.

Finally, Dr. Matsumoto presented his study. Association between intraoperative hyperglycemia and postoperative end-organ dysfunctions after cardiac surgery: a retrospective observational study. His findings showed that the intraoperative GE index, the product of the magnitude and duration of a BG concentration ≥ 180 mg/dL, was an independent predictor of end-organ damage within 72 hours after surgery, defined as a composite event of AKI, POCD, MI and PMV. Dr. Matsumoto’s presentation led to a very intense discussion with questions about perioperative insulin dosing, preoperative glycemic control, use of medications for diabetic patients and intraoperative drugs that may cause a rise in blood glucose, and Dr. Matsumoto answered all questions carefully. This topic was a real eye-opener for us and we are very grateful to him for sharing this valuable research with us and we are looking forward to the next exchange.

Three speakers presented their research in this workshop, and other participants asked questions of their own interest about their presentations. I thought it was a good chance to present their research and also to get professional advice to think more deeply about their own research.

At the end we congratulated the graduating students, and these two students also expressed their feelings. I believe the next seminar will be even more exciting.

Jingwen Fu

Histidine-rich glycoprotein as a novel predictive biomarker of postoperative complications in intensive care unit patients: a prospective observational study

2022.08.28 お知らせ

Histidine-rich glycoprotein as a novel predictive biomarker of postoperative complications in intensive care unit patients: a prospective observational study.

Oiwa M, Kuroda K, Kawanoue N, Morimatsu H.BMC Anesthesiol. 2022 Jul 20;22(1):232. doi: 10.1186/s12871-022-01774-7.PMID: 35858852 Free PMC article.

MAP seminar

2022.08.12 お知らせ

10th MAP Seminar Report

Date: august 12, 2022

Speaker: Dr. Masahiko Oiwa, Dr. Guo Yusheng and Dr. Kimura Satoshi

We conducted our 10th MAP seminar on August 12, 2022.

15 Members participated in this seminar.

The first speaker was Dr. Masahiko Oiwa.

He research topic is “Histidine-rich glycoprotein as a novel predictive biomarker of postoperative complications in intensive care unit patients A prospective observational study”

He chose ICU patients after surgery and the HGR levels on POD1 in the patients with or without postoperative complications was her outcome. IN this study we learned the HRG levels on POD 1 was lower in patients who developed postoperative complications and the abililty of HRG to predict postoperative complications was superior than CRP and WBC. We believe his results are useful in ICU clinic work. The audiences who doing clinical studies actively joined in the discussion.

The second speaker was Guo yusheng.

The topic of his research was “Early fluid balance and hemodynamics are associated with 90-day mortality in patients undergoing continuous renal replacement therapy”His research was a complex because he simultaneously focusses on MAP and fluid. Both of them associated with patient mortality but the two factor can influence each other. Therefore Dr.Guo tracked 72-h fluid management and MAP at the same time to prove the positive fluid management associate with mortality was more evident in patients without shock. In addition, in this research we also witnessed that the reduce of daily fluid balance did not change stable hemodynamics. This result may impact future studies. The audiences felt interested in this research, they gave many good suggestions and questions.

The third speaker was Dr. Kimura Satoshi

The topic of his report was “Encouragement of Clinical research how to start ”

He is an experienced Clinical Investigator. In his report we learn a Completed research system from find clinical questions to write paper. In addition, he also teaches us many statistics experience such as multiple testing problem hypothesis testing. ALL audiences were enjoyed his reported and Dr. Kimura explained every question professionally. We look forward to his next report.

During the time MAP seminar, three speakers made presentations in English around clinical study, sharing their studies and research experience. The audiences took an active part in the discussion and ask question about the research and report, and we learned a lot about the clinical researches.

Professor Morimatsu explained each study carefully, and supplemental explained every doubts about their studies, helped researchers answer question completely and lead students to fully understand. All the participators learned and discussed in a lively environment and got professional suggest. We are highly looking forward learn more knowledge in the next MAP seminar.

LiSA

2022.08.01 お知らせ

https://twitter.com/MEDSi_han/status/1553901150415400962

Intrathecal Administration of the α1 Adrenergic Antagonist Phentolamine Upregulates Spinal GLT-1 and Improves Mirror Image Pain in SNI Model Rats

2022.07.17 お知らせ

                 Intrathecal Administration of the α1 Adrenergic Antagonist Phentolamine Upregulates Spinal GLT-1 and Improves Mirror Image Pain in SNI Model Rats.               

 

. 2022 Jun;76(3):255-263.

doi: 10.18926/AMO/63719.

Intrathecal Administration of the α1 Adrenergic Antagonist Phentolamine Upregulates Spinal GLT-1 and Improves Mirror Image Pain in SNI Model Rats

Affiliations

Temporary hypotension and ventilation difficulty during endoscopic injection sclerotherapy for esophageal varices in a child with Fontan circulation: a case report

お知らせ

                 Temporary hypotension and ventilation difficulty during endoscopic injection sclerotherapy for esophageal varices in a child with Fontan circulation: a case report.               

. 2022 Jul 5;8(1):48.

doi: 10.1186/s40981-022-00538-z.

Temporary hypotension and ventilation difficulty during endoscopic injection sclerotherapy for esophageal varices in a child with Fontan circulation: a case report

Affiliations

Depolarization time and extracellular glutamate levels aggravate ultraearly brain injury after subarachnoid hemorrhage

2022.06.26 お知らせ

Depolarization time and extracellular glutamate levels aggravate ultraearly brain injury after subarachnoid hemorrhage.

Murai S, Hishikawa T, Takeda Y, Okura Y, Fushimi M, Kawase H, Takahashi Y, Kidani N, Haruma J, Hiramatsu M, Sugiu K, Morimatsu H, Date I.
Sci Rep. 2022 Jun 17;12(1):10256. doi: 10.1038/s41598-022-14360-1.PMID: 35715559 Free PMC article.

鹿田

2022.06.11 お知らせ

MAP seminar

2022.06.10 お知らせ

9th MAP Seminar Report

Date: June 10, 2022

Speaker: Dr. Okura Yasuko, Dr. Li yaqiang and Dr. Isoyama Satoshi

We conducted our 9th MAP seminar on June 10, 2022.

15 Members participated in this seminar.

 

The first speaker was Dr. Okura Yasuko.

Her research topic is “Neuroprotective effects of Magnesium in cardiac arrest model of rats”

She used SD rats to make the cardiac arrest model and after treatment of Magnesium she checked the extracellular glutamate level. We learned a lot about the animal model making as well as some techniques about basic experiments.

The audiences actively joined in the discussion part and raised a lot of interesting questions.

Professor Morimatsu gave answers to the questions in detail to help the students better understand the research content.

 

The second speaker was Dr. Li yaqiang.

The topic of his research was “The protective effect of Carbamazepine on hemorrhagic shock and resuscitation induced Acute lung injury in rats”

He used SD rats to make the hemorrhagic shock and resuscitation model, after that he examined pathological analysis, wet weight to dry weight ratio of lung tissue, neutrophil count, inflammatory factor assay, and lung tissue autophagy-related protein assay to find out the relationship between carbamazepine and inflammation as well as autophagy.

The audiences felt interested in this research, they gave many good suggestions and questions.

 

The third speaker was Dr. Isoyama Satoshi

The topic of his research was “Relationship between partial carbon dioxide pressure and strong ions in humans: A retrospective study”

He conducted a retrospective study on the relationship between pCO2 and SID as well as other strong ion concentrations. Separately he set three datasets and made analyses. This is a very new and interesting subject, professor gave a high evaluation. This research is helpful for clinical work.

 

During the MAP seminar, three speakers made an excellent presentations in English, sharing their currently work and achieved results, meanwhile, the audiences took an active part in the discussion about the research, and they learned a lot about the clinical as well as basic researches.

Professor Morimatsu carefully analyzed each study, and answered everyone’s doubts about the current studies, helping researchers and students to better understand.

All the participators communicated and learned in a relaxed and pleasant environment. We are highly looking forward to the next MAP seminar.

20th MOMO seminar

2022.05.22 お知らせ

第20回 MOMOセミナー開催報告書 (2022年5月20日(金) 19時~)

文責: 山﨑 友輔 (福山市民病院 麻酔科)

 

・2022年5月20日(金)の19時からZOOM meeting上で、第20回 MOMOセミナーを開催しました。今回のセミナーは ① コーディネーター卒業講演と② 麻酔科専門医試験口頭試問勉強会を実施しました。

 

① MOMOセミナーコーディネーター卒業講演 (担当: 山﨑, 鄭先生 (岡山赤十字病院))

・今回のMOMOセミナーをもって、私山﨑と鄭先生はセミナーのコーディネーターを卒業し、新しい先生方にその役割を引き継ぎます。今回森松教授には卒業に際し、MOMOセミナーで卒業講演の機会を設けていただきました。私は麻酔科医としてのこれまでの経歴、今後の目標・抱負等を語らせていただきました。私自身は学生時代~初期研修医の途中までは麻酔科は全く志望していませんでしたが、初期研修病院のさいたま赤十字病院で出会った麻酔科の先生方に麻酔科学の魅力を教えていただき、その虜となって今に至ります。麻酔科医としての最初の1年目は岡山大学病院で仕事をさせていただきました。大学病院ならではの様々な症例に対して、何度も自分の知識・実力不足を実感し、周囲にも沢山迷惑をかけてしまいました。そんな中でも最後まで根気強く向き合ってくださった指導医や支えてくれた同期、改めて周りの人々の存在に恵まれていたと痛感しております。今後は自分自身麻酔科医として更に修練を積みながら、自分より下の先生方に麻酔科の魅力を伝えることのできる存在になれるよう努力していきたいです。同期の鄭先生も自身のこれまでの経緯や今後のキャリアパス等、しっかりと語られていました。同期として、私自身も良い刺激をもらいました。

 

② 麻酔科専門医試験口頭試問勉強会 (参加者一同)

・今回この企画は3回目となります。今回も参加者一同で、専門医口頭試問の公開されている過去問を検討しました。今回、この企画に初めて参加された先生方もいらっしゃいました。口頭試問は実際に私たちが日常診療で遭遇しうる症例、術中の麻酔管理、トラブルに対する対処法等を問われます。知識として理解していることでもそれを他者に伝えること、言語化することの難しさを多くの先生方が実感されていました。また普段何気なく行なっている診療行為に対しても、その根拠を聞かれると、回答に困ることもあるとの意見もありました。

 

③ デブリーフィング (希望者)

・セミナー終了後は、希望者でデブリーフィングを行いました。デブリーフィングでは、他病院の学年の近い先生方と交流のできる貴重な場です。この4月から新天地で活躍されている先生方も多く、互いの近況報告であったり、日常診療で抱いた疑問等を話し合ったりしました。私自身もこのデブリーフィングでは他の先生方の話から知らなかった知見を得たり、自分の疑問や悩みを聞いていただいたり、他の先生方の活躍に刺激とモチベーションをいただいたりと有意義な時間を過ごしています。